Support for APD: Understanding Aspirin-Exacerbated Respiratory Disease and How to Manage It

When you have Aspirin-Exacerbated Respiratory Disease, a chronic condition where NSAIDs like aspirin trigger severe breathing and sinus reactions. Also known as AERD, it’s not just an allergy—it’s a systemic inflammatory disorder that affects the lungs, nose, and sinuses. People with AERD often have asthma, recurring nasal polyps, and chronic congestion that doesn’t respond to typical allergy treatments. Many mistake it for regular allergies or sinus infections, but it’s a distinct syndrome tied to how the body processes certain painkillers.

This condition doesn’t show up on standard allergy tests. Instead, it’s diagnosed by a pattern: after taking aspirin or other NSAIDs, you get wheezing, nasal blockage, or even full asthma attacks. It’s most common in adults who developed asthma in their 20s or 30s, especially those with a history of nasal polyps. The link between NSAID sensitivity, a key trigger for AERD symptoms and respiratory flare-ups is well-documented. Even ibuprofen or naproxen can set off reactions in some people. Avoiding these drugs isn’t just about comfort—it’s about preventing dangerous breathing episodes.

There’s hope, though. One proven treatment is aspirin desensitization, a medical procedure where patients are gradually exposed to aspirin under supervision to reduce sensitivity. Many who complete this process see fewer polyps, less need for surgery, and better asthma control. Biologics like dupilumab are also helping those who don’t respond to traditional approaches. Managing AERD isn’t about avoiding everything—it’s about knowing what works and what to steer clear of.

The posts below cover real-world strategies for living with this condition. You’ll find guides on identifying hidden NSAIDs in medications, understanding how biologics change the game, and what to do when a flare-up hits. There’s also practical advice on managing related issues like chronic sinus infections and steroid dependence. Whether you’re newly diagnosed or have been struggling for years, these resources give you the tools to take back control—without guesswork.